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WSDL 1.2 The W3C formed the Web Services Description working group in 2002 and had produced signi cant deliverables by summer 2003. In addition to a requirements and a usage scenarios document, the group is creating the WSDL 1.2 speci cation. The current form of the speci cation is in three parts. WSDL Part 1: Core Language de nes the overall document framework in terms of an abstract component model modeled as an XML Infoset. WSDL Part 2: Message Patterns de nes the supported primitive message combinations used to support a Web service operation. Message patterns are binding independent and are de ned in terms of sequence, direction, cardinality (single or multicast), and potential faults. WSDL 1.3: Bindings de nes WSDL protocol extensions to use with SOAP and HTTP, along with an extension to use with the MIME message format. The WSDL 1.2 speci cation has made some changes relative to WSDL 1.1. Operator overloading was possible in 1.1, and this feature has been removed in 1.2. The <portType> element has been renamed <interface>, and interface inheritance is supported. The <port> element has been renamed <endpoint>. WSDL 1.2 is also de ning a mechanism to describe extensibility in terms of features and properties. Features are described in SOAP 1.2. Features are de ned abstractly, and their role is to introduce a new capability, such as security or correlation, which extends the SOAP processing model. Properties are concrete extension elements that support a given feature. Hence, properties and features should enable WSDL 1.2 to describe extended distributed processing functionality beyond the basic SOAP features. 14.2.6 Discovery Protocols

of the neural crest, some SA cells arrive in the adrenal anlagen around embryonic day 105 and are arrested there both developmentally and functionally (a process termed neoteny), while other SA cells continue to migrate and differentiate eventually into sympathetic neurons [Anderson and Axel, 1986; Anderson, 1989, 1993] In the adrenal anlagen, these SA cells differentiate into two distinct catecholaminergic chromaf n cell types, which are characterized as either noradrenergic or adrenergic, that is, each of these related, yet distinct, cell types synthesizes and secretes either noradrenaline (norepinephrine, NE) or adrenaline (epinephrine, E) [Moro et al, 1990; Weiss et al, 1996] Recent studies indicate that the expression of noradrenaline in the NE cells during differentiation is independent of the presence of glucocorticoids (synthesized in the neighboring adrenal cortex).

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By contrast, the conversion of NE to E, which requires the functional expression of phenylethanolamine-N -methyltransferase (PNMT), the nal enzyme in the catecholamine synthesizing cascade, might require induction by glucocorticoids, such as dexamethasone [Doupe et al, 1985; Anderson and Michelson, 1989; Finotto et al, 1999; Wong, 2003] The details of the chromaf nergic differentiation process, as fascinating as they may be, are beyond the scope of this article and can be found in a recent review [Huber et al, 2002] Suf ce it to say that, regardless of the effect of glucocorticoids, homotypic and heterotypic 3-D cell-cell interactions during organogenesis appear to be pivotal for the organotypic differentiation of the parenchymal cells in the adrenal medulla [Lelkes and Unsworth, 1992].

PIT Using Rollback. For this approach, the LRM will put the database of ine; will undo all active and completed transactions from the current time to a PIT; and then will put the database back online. PIT Using Roll Forward. For this approach, the LRM will put the database of ine; will restore the database from the most recent complete cold backup; will roll all completed transactions prior to the PIT forward; and will put the database back online.

Chromaf n cells have been used for many decades as an easily available model system for studying mechanisms of neurotransmitter synthesis and release, speci cally of cholinergic neuronal or neuroendocrine stimulus-secretion-synthesis coupling Indeed, a recent PubMed search for chromaf n cells (August 2005) revealed some 3900 relevant hits In contrast to bona de chromaf n cells, PC12 pheochromocytoma cells are predominantly dopaminergic, that is, they express tyrosine hydroxylase (TH) and dopamine- -hydroxylase (DBH), and synthesize and secrete small amounts of NE [Greene and Tischler, 1976] In the hands of most (but not all) investigators, PC12 cells do not spontaneously express PNMT or epinephrine, thus suggesting that these cells originated from the NE phenotype of chromaf n cells In the past 25 years PC12 cells have become an enormously popular model, mainly for studying fundamental mechanisms of neuronal differentiation and mechanisms of neurotransmitter synthesis and release.

Currently (August 2005) there are more than 8500 PubMed citations describing a plethora of physiologic and molecular aspects of these cells, including the inducibility of the expression of functional PNMT [Byrd et al, 1986; Kim et al, 1993; Ebert et al, 1997; Lelkes et al, 1998, Unsworth and Lelkes, 1998b] PC12 cells are in a unique position in that they maintain some of the features of the bipotentiality of fetal/embryonic SA cells, with the added advantage that PC12 cells are readily available and rather easy to culture Thus, depending on the appropriate environmental cues, PC12 cells can differentiate along either the sympathetic neuronal or the neuroendocrine, chromaf nergic pathway For.

Excel 97 gives me a compile error when I write UserForm1.Show vbModeless. How can I make the form modeless in Excel 2002, while allowing it to remain modal in Excel 97

return $ctx->error ($builder->errstr); } # Append the build results to the overall results $res .= $out; } # Return the text for the template return $res; }

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